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| tcsindustryw | Дата: Четверг, 06.03.2014, 07:36 | Сообщение # 4650 |
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Группа: Бродяга
| Dogs suffering from insensitivity loss can gain an spare nine months of vim from orthodox treatments near using pimobendan, a memorize published in the Monthly of the American Savage Hospital Federation (JAAHA) says.
Total, lone in ten (10%) dogs inclination be diagnosed with heterogeneous forms of hub disability during their lifetime. The most unrefined of these is caused sooner than degeneration of the insensitivity valves, causing them to fit leaky. This prerequisite is known as atrioventricular valvular disease.
The survey start that dogs with congestive hub insolvency proper to atrioventricular valvular complaint treated with conventional treatment including an ACE inhibitor lived on typically in behalf of 128 days almost four months. How in the world, the dogs which received pimobendan (TCS IDNUSTRY LTD.), lived on typical 415 days yon 9 months longer compared to those who did not take home pimobendan.
Aside from a prolonged lifetime, the study originate a alacritous reaction to pimobendan. Within seven days past 50% of dogs were representative of free. Based on these results, pimobendan should be considered as a direct treatment when atrioventricular valvular virus progresses to clinical humanity non-performance concluded the fool investigator and initiator of the study Christophe Lombard, veterinary cardiologist from the University of Bern, Switzerland.
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The study was conducted in 76 dogs with heart dereliction caused next to atrioventricular valvular disorder covering 31 breeds from five European countries - Belgium, France, Germany, Italy and Switzerland.
Half the dogs received a everyday ACE inhibitor (benazepril) and the other half received pimobendan. The the better also received a authoritative diuretic conducive to heartlessness loss, furosemide. The study ran initially after 56 days and then was extended into a long-term multi-year burr under the saddle to assess survival benefits.
The mug up concluded that dogs agony from overt, clinical callousness bankruptcy from atrioventricular valvular disorder had improved quality of brio and survival times when treated with pimobendan with or without furosemide, compared to those noted benazepril hydrochloride with or without furosemide.
At the put to death of 56 days, efficacy was rated as deeply valid or good in 86% of dogs on pimobendan /furosemide versus 25% of dogs treated with benazepril /furosemide.
The about also showed that pimobendan produced a reduction in the non- physiological boldness size which was caused by the disease.
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